Adjuvant osimertinib delivers sustained long term survival benefit in EGFR mutated NSCLC
Published on 28 September 2026
Dr Roy Herbst speaks to ecancer about updated long-term results from the phase III ADAURA trial.
The results further demonstrate the survival benefit of three years of adjuvant osimertinib in patients with resected EGFR-mutated stage IB-IIIA NSCLC.
In the overall population, the 8-year overall survival rate was 79% with osimertinib versus 64% with placebo, with a 48% reduction in the risk of death.
In patients with stage II-IIIA disease, the 8-year survival rate was 74% versus 58%.
Dr Herbst explores the durability of the survival benefit following completion of adjuvant treatment and outcomes across predefined patient subgroups.